Located in the rolling hills of middle Tennessee, Lewisburg took its name from the explorer Meriwether Lewis. By 1838 the town was supporting a newspaper and a bank. The downtown area is modeled after many small southern towns with a courthouse in the center of the square surrounded by retail and commercial businesses. Shopping centers are located at the east and west ends of town.

Several historic neighborhoods still exist along with numerous churches many of which are located with a few blocks of the Lewisburg square and provide meeting places for civic organizations or community functions.